后腹腔镜肾部分切除术对肾门肿瘤患者并发症、Cor、AD及NE表达水平的影响

Effect of retroperitoneal laparoscopic partial nephrectomy on complications,Cor,AD and NE levels in patients with renal hilum tumor

目的分析后腹腔镜肾部分切除术对肾门肿瘤患者并发症、皮质醇(Cor)、肾上腺素(AD)和去甲肾上腺素(NE)表达水平的影响。方法选择85例肾门肿瘤患者,分为观察组43例和对照组42例。对照组给予开放肾部分切除术,观察组则行后腹腔镜肾部分切除术治疗。比较两组患者预后情况及术前术后Cor、AD及NE表达水平。结果两组患者术前的Cor、AD、NE水平比较,差异均无统计学意义(t分别=0.64、0.06、0.06,P均>0.05),观察组术后Cor、AD水平明显高于对照组(t分别=8.87、3.90,P均<0.05),但两组术后NE水平比较,差异无统计学意义(t=0.80,P>0.05)。观察组术后并发症的总发生率明显低于对照组,差异有统计学意义(χ2=16.83,P<0.05)。结论采用后腹腔镜肾部分切除术治疗肾门肿瘤患者的临床治疗效果较开放肾部分切除术更好,术后并发症较少。

Objective To analyze the effect of retroperitoneal laparoscopic partial nephrectomy on complications,cortisol(Cor),adrenaline(AD)and norepinephrine(NE)levels in patients with renal hilum tumor.Methods Totally 85 patients with renal hilum tumor were divided into control group(42 cases)and observation group(43 cases).The control group received open partial nephrectomy,while the observation group received retroperitoneal laparoscopic partial nephrectomy.The prognosis of the two groups was compared after operation.The Cor,AD and NE levels before and after treatment between two groups were compared too.Results Before treatment,the differences in Cor,AD and NE levels between two groups were not statistically significant(t=0.64,0.06,0.06,P>0.05).The levels of Cor and AD after treatment in the observation group were significantly lower than those in the control group(t=8.87,3.90,P<0.05),while the NE level between two group was not statistically different(t=0.80,P>0.05).The total incidence of postoperative complications in the control group was significantly higher than that in the observation group(χ~2=16.83,P<0.05).Conclusion Retroperitoneal laparoscopic partial nephrectomy is effective in the treatment of renal hilum tumor patients with fewer postoperative complications.