老年社区获得性重症肺炎患者肺部感染控制窗影响因素与预后

Influencing Factors and Prognosis of Pulmonary Infection Control Window in Elderly Patients with Community-Acquired Severe Pneumonia

目的分析影响老年社区获得性重症肺炎患者肺部感染控制(PIC)窗的因素,探讨肺部感染控制窗对患者预后的影响。方法对268例经治疗出现PIC窗的老年社区获得性重症肺炎患者进行调查,采用单因素分析和Logistic多因素回归分析对PIC窗与相关因素之间的关系进行分析,采用对照研究的方法,探讨短PIC窗和长PIC窗对患者预后的影响。结果 Logistic多因素回归分析结果表明年龄>75岁、营养不良、慢性阻塞性肺疾病、多重耐药是影响肺部感染控制窗的独立危险因素。对照研究结果表明短PIC窗患者的住院时间、病死率显著高于长PIC窗患者(P<0.05)。结论高龄、营养不良、慢性阻塞性肺疾病、多重耐药可能缩短PIC窗,而延长PIC窗有利于患者的预后。

Objective To analyze the influencing factors of pulmonary infection control(PIC) window in elderly patients with community-acquired severe pneumonia, and to explore the effect of PIC window on the prognosis of patients. Methods A total of 268 elderly patients with community-acquired severe pneumonia who had PIC window after treatment were investigated. The relationships between PIC window and related factors were analyzed by univariate analysis and Logistic multivariate regression analysis, and the effects of short PIC window and long PIC window on the prognosis of patients were explored using the method of control study. Results Logistic multivariate regression analysis showed that age >75 years old, malnutrition, chronic obstructive pulmonary disease, and multi-drug resistance were independent risk factors affecting PIC window. The results of the control study showed that the hospitalization time and mortality rate of patients with short PIC window were significantly higher than those of patients with long PIC window(P<0.05).Conclusions Advanced age, malnutrition, chronic obstructive pulmonary disease, and multi-drug resistance may shorten the PIC window, and prolonging the PIC window is beneficial to the prognosis of patient.