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不同镇痛方法对老年膝关节置换术患者术后疼痛和功能恢复的影响 被引量:16

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摘要 目的对比分析连续股神经阻滞(CFNB)、CFNB联合关节周围浸润镇痛(PLIA)两种镇痛方法对老年全膝关节置换术(TKA)患者术后疼痛和功能恢复的影响。方法因膝骨关节炎(KOA)或类风湿关节炎(RA)拟行TKA治疗的96例(96膝)老年患者按手术顺序编号后以随机数表法分为A、B组,各48例。A组给予CFNB,B组给予CFNB联合PLIA。对比两组镇痛效果、术后应激与炎症反应、功能恢复情况,并评价安全性。结果与A组相比,B组术后静息2、6、12、24、48 h及术后主动活动12、24、48 h患侧膝关节疼痛视觉模拟评分(VAS)均显著降低(P<0.05)。两组术后6 h血清皮质醇、醛固酮及C反应蛋白(CRP)含量均较术前明显升高(P<0.05),但B组明显低于A组(P<0.05)。与A组相比,B组术后被动屈膝90°时间、开始行直腿抬高锻炼时间显著缩短(P<0.05);与术前比较,两组术后72 h时膝关节活动度(ROM)及美国膝关节协会(KSS)评分明显增高(P<0.05),但组间ROM差异不显著(P>0.05),KSS评分差异显著(P<0.05)。A、B组药物相关不良反应率分别为8.33%、12.50%,未见统计学差异(P>0.05)。结论老年TKA患者给予CFNB联合PLIA,术后静息、主动活动镇痛效果均突出,有助于抑制术后应激与炎症反应,从而有效缩短锻炼及膝关节功能恢复时间。
出处 《中国老年学杂志》 CAS 北大核心 2020年第6期1224-1227,共4页 Chinese Journal of Gerontology
基金 海南省医药卫生科研项目(No.1801032021A2001)
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