期刊文献+

子宫内膜异位症激素治疗新进展 被引量:16

下载PDF
导出
摘要 子宫内膜异位症(EMs)是一种激素依赖性良性疾病。临床一线用药可缓解部分患者的痛经症状,但对某些患者的治疗效果不佳。现阶段针对雌孕激素与其受体的研究,对GnRH受体激动剂(GnRH-as)与受体拮抗剂(GnRH-ant)的研发,以及对孤儿核受体的研究,都展现出EMs治疗的新进展。
出处 《现代妇产科进展》 CSCD 北大核心 2020年第3期230-232,236,共4页 Progress in Obstetrics and Gynecology
  • 相关文献

参考文献3

二级参考文献31

  • 1Xu J,Wu R C,O'malley B W.Normal and cancer-related functionsof the p160 steroid receptor co-activator (SRC) family [J].Nat Rev Cancer,2009,9(9):615.
  • 2Nguyen H D,Phan T T,Carraz M,et al.Estrogen receptor α/β-co-factor motif interactions;interplay of tyrosine 537/488 phosphoryla-tion and LXXLL motifs[J].Mol Biosyst,2012,8(12):3134.
  • 3Bolt M J,Stossi F,Newberg J Y,et al.Coactivators enable glucocor-ticoid receptor recruitment to fine-tune estrogen receptor transcrip-tional responses[J].Nucleic Acids Res,2013,41(7):4036.
  • 4York B,O' malley B W.Steroid receptor coactivator (SRC) family:masters of systems biology[J].J Biol Chem,2010,285(50):38743.
  • 5Lanz R B,Bulynko Y,Malovannaya A,et al.Global characterization of transcriptional impact of the SRC-3 coregulator[J].Mol En-docrinol,2010,24(4):859.
  • 6Fenne I S,Helland T,Flgtgeng M H,et al.Downregulation of steroid receptor coactivator-2 modulates estrogen-responsive genes and stimulates proliferation of mcf-7 breast cancer cells[J].PLoS One,2013,8(7):e70096.
  • 7Johnson A B,O' malley B W.Steroid receptor coactivators 1,2,and 3:critical regulators of nuclear receptor activity and steroid receptor modulator (SRM)-based Cancer therapy[J].Mol Cell Endocrinol,2012,348(2):430.
  • 8Moi L L,Flglgeng M H,Gjerde J,et al.Steroid receptor coactivators,HER-2 and HER-3 expression is stimulated by tamoxifen treatment in DMBA-induced breast cancer[J].BMC Cancer,2012,12:247.
  • 9Palmieri C,Gojis O,Rudraraju B,et al.Expression of steroid recep-tor coactivator 3 in ovarian epithelial cancer is a poor prognostic factor and a marker for platinum resistance[J].Br J Cancer,2013,108(10):2039.
  • 10Thigpen T,Dubois A,Mcalpine J,et al.First-line therapy in ovarian cancer trials[J].Int J Gynecol Cancer,2011,21(4):756.

共引文献29

同被引文献222

引证文献16

二级引证文献23

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部