美罗培南不同给药方式对重症监护病房脓血症患者凝血功能的影响

Effects of Different Administration Modes of Meropenem on Coagulation Function in Patients with Sepsis in Intensive Care Unit

目的探讨美罗培南不同给药方式对重症监护病房脓血症患者凝血功能的影响。方法选取选取2017年1月至2018年1月在大连市中心医院急诊ICU就诊的80例脓毒血症患者,按照美罗培南不同给药方式的不同,静脉滴注美罗培南为对照组40例,微量注射泵行持续泵入美罗培南为试验组40例,比较两组患者治疗一段时间后的凝血功能。结果试验组凝血功能指标优于对照组,差异有统计学意义(P<0.05)。结论微量注射泵行持续泵入美罗培南其效果更加,值得在临床推广。

Objective To explore the effect of meropenem on coagulation function in patients with abscess in intensive care unit. Methods Choose from January 2017 to January 2018 in dalian center hospital emergency icu treatment, 80 cases of patients with sepsis, the different methods of drug delivery, according to various beauty e.faecalis intravenous drip beauty e.faecalis as control group 40 cases, trace injection pump line continuous pumping beauty e.faecalis as experimental group 40 cases, compared two groups of patients after a period of time of blood coagulation function. Results The coagulation function index of the experimental group was better than that of the control group, and the difference was statistically significant(P<0.05). Conclusion The effect of continuous infusion of microinjection pump into meropenem is more effective and worthy of clinical promotion.