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转移性结直肠癌经含氟尿嘧啶类药物联合化疗控制后行卡培他滨维持治疗的可行性分析 被引量:2

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摘要 目的探究转移性结直肠癌患者经含氟尿嘧啶类药物联合化疗控制后行卡培他滨维持治疗的效果,为临床提供指导。方法随机抽取2017年1月至2019年4月我院92例转移性结直肠癌患者为观察对象,经含氟尿嘧啶类药物联合化疗治疗后,92例患者病情均得到控制,其中50例患者实施卡培他滨维持治疗(观察组),42例患者未接受任何治疗(对照组),对比两组患者的无进展生存期、生存质量评分、不良反应发生率。结果观察组患者无进展生存期[(11.24±0.61)个月]多于对照组[(7.65±0.42)个月],且生存质量评分[(72.36±3.41)分]高于对照组[(68.42±3.42)分],P <0.05;观察组患者白细胞减少、手足综合征发生率高于对照组,P <0.05。结论对经含氟尿嘧啶类药物联合化疗控制后转移性结直肠癌患者实施卡培他滨维持治疗具有较好的效果,可延长患者无进展生存期,提高其生存质量,且患者耐受性良好。
作者 张红林
出处 《中国医药指南》 2020年第5期156-157,共2页 Guide of China Medicine
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