非肥胖2型糖尿病合并下肢动脉硬化患者血脂水平的变化及临床意义

Changes and clinical significance of blood lipid level in non-obese type 2 diabetes mellitus patients with lower extremity arteriosclerosis

目的探讨非肥胖2型糖尿病合并下肢动脉硬化患者血脂水平的变化及临床意义。方法收集2017年1月至2019年1月我院收治的120例非肥胖2型糖尿病患者的临床资料,根据有无下肢动脉硬化将其分为研究组(合并下肢动脉硬化)和对照组(未合并下肢动脉硬化),每组60例。比较两组患者的血压、血糖、肝功能及血脂指标。结果研究组的SBP、HOMA-IR均高于对照组(P<0.05)。研究组的TC、TG、LDL-C水平及AIP均显著高于对照组(P<0.05)。结论合并下肢动脉硬化的非肥胖2型糖尿病患者普遍存在血脂异常情况,临床应及早实施有针对性的干预,以改善患者的预后。

Objective To investigate the changes and clinical significance of blood lipid level in non-obese type 2 diabetes mellitus patients with lower extremity arteriosclerosis.Methods The clinical data of 120 patients with non-obese type 2 diabetes mellitus admitted in our hospital from January 2017 to January 2019 were collected.According to the presence or absence of lower extremity arteriosclerosis,the patients were divided into study group(with lower extremity arteriosclerosis) and control group(without lower extremity arteriosclerosis),with 60 cases in each group.The indexes of blood pressure,blood glucose,liver function and blood lipid were compared between the two groups.Results The SBP and HOMA-IR in the study group were higher than those in the control group(P<0.05).The levels of TC,TG,LDL-C and AIP in the study group were significantly higher than those in the control group(P<0.05).Conclusion Dyslipidemia is common in patients with non-obese type 2 diabetes mellitus and lower extremity arteriosclerosis.Targeted intervention should be carried out in clinic as early as possible to improve the prognosis of the patients.