中西医结合治疗慢性肾脏病急性肾损伤的临床效果

Clinical effect of integrated traditional Chinese and western medicine on chronic kidney disease with acute renal injury

目的探讨中西医结合治疗慢性肾脏病急性肾损伤(CKD-AKI)的临床效果。方法选取2017年12月至2018年12月我院收治的CKD-AKI患者98例,随机分为对照组(49例)和研究组(49例)。对照组给予前列腺素E1治疗,研究组在此基础上给予黄芪注射液治疗。比较两组治疗前、后的肾功能指标水平及临床疗效。结果治疗后,两组β2-MG、Scr、BUN、Cys C、NGAL、KIM-1水平均低于治疗前,且研究组显著低于对照组(P<0.05)。研究组治疗总有效率显著高于对照组(P<0.05)。结论中西医结合治疗CKA-AKI的效果显著,能够有效改善患者肾功能,值得临床推广应用。

Objective To explore the clinical effect of integrated traditional Chinese and western medicine on chronic kidney disease with acute renal injury(CKD-AKI).Methods Ninety-eight patients with CKD-AKI admitted in our hospital from December 2017 to December 2018 were randomly divided into control group(49 cases) and study group(49 cases).The control group was treated with prostaglandin E1,while the study group was treated with astragalus injection on this basis.The renal function indexes before and after treatment and clinical effect between the two groups were compared.Results After treatment,the levels of β2-MG,Scr,BUN,CysC,NGAL and KIM-1 in the two groups were lower than those before treatment,and those in the study group were significantly lower than the control group(P<0.05).The total effective rate of treatment in the study group was significantly higher than that in the control group(P<0.05).Conclusion The integrated traditional Chinese and western medicine on CKD-AKI has significant effect,it can effectively improve the renal function of patients,which is worthy of clinical promotion and application.