酵母长链非编码RNA研究进展

Recent advances in long non-coding RNA of yeast

长链非编码RNA是一类在生物体中广泛存在且不编码蛋白质的功能性RNA分子,直接在RNA水平发挥作用,影响生物体的生命活动。随着研究技术的进步,真菌中长链非编码RNA的研究稳步增加,酿酒酵母和粟酒裂殖酵母尤为常见。文章主要对酿酒酵母和粟酒裂殖酵母中的长链非编码RNA进行分类,并描述其作用方式及其参与的生物学功能,以期为进一步研究酵母长链非编码RNA提供一定的理论与研究基础。

Long non-coding RNA is a kind of functional RNA molecule which is widely existed in organisms and does not encode proteins.It plays a role directly at the RNA level and affects the life activities of organisms.With the development of research technology,the research on long non-coding RNA in fungi has been increasing steadily.This article mainly classifies long non-coding RNAs in Saccharomyces cerevisiae and Schizosaccharomyces pombe,and describes their mode of action and the biological functions they participate in,in order to provide some theory and further research for yeast long non-coding RNA research foundation.