抗生素种类及营养状况对伪膜性肠炎首发时间的影响

Influence of the types of antibiotics and nutritional status on the starting time of pseudomembranous colitis

目的探讨应用抗生素种类及患者营养状况对伪膜性肠炎首发时间的影响。方法回顾性分析56例伪膜性肠炎患者应用抗生素种类及营养状况与伪膜性肠炎首发时间的关系。结果应用3种以下抗生素组和3种及以上抗生素组患者伪膜性肠炎的首发时间分别为(14.2±4.4)d和(11.8±4.7)d,差异无统计学意义(P>0.05);营养正常组伪膜性肠炎的首发时间(15.3±4.4)d较营养不良组患者(9.1±2.2)d延迟,差异有统计学意义(P<0.05)。结论应用抗生素均需及早警惕伪膜性肠炎发生;营养不良患者发生伪膜性肠炎时间早,改善营养状况是延迟伪膜性肠炎发生的重要辅助治疗。

Objective To investigate the influence of the types of antibiotics and nutritional status on the starting time of pseudomembranous colitis(PMC)by retrospective analysis.Methods A total of 56 cases with PMC were admitted.The influence of the types of antibiotics and nutritional status on the starting time of PMC were analyzed.Results There were no significant differences in the starting time of PMC between the group in which patients used less than three types of antibiotics(14.2±4.4)d and the group in which patients used three or more than three types of antibiotics(11.8±4.7)d.The starting time of PMC in the normal nutrition group(15.3±4.4)d was significantly later than that of the malnutrition group(9.1±2.2)d.Conclusion Close observation will be necessary during antibiotic therapy.Improve the nutrition status will be helpful to reduce the occurrence of PMC.