脑苷肌肽辅助治疗老年脑梗死患者的临床观察

Clinical observation of cerebroside carnosine in the treatment of elderly patients with cerebral infarction

目的探讨脑苷肌肽辅助治疗老年脑梗死患者的有效性。方法选取本院2017年5月至2018年6月收治的62例老年脑梗死患者,根据入院时间分为观察组与对照组,各31例。观察组给予常规治疗+脑苷肌肽辅助治疗,对照组给予常规治疗,对比两组治疗效果。结果观察组治疗后高/低密度脂蛋白胆固醇比值(LDL-C/HDL-C)、超敏C反应蛋白(hs-CRP)、降钙素原(PCT)、胱抑素C(Cys-C)、同型半胱氨酸(Hcy)均低于对照组(P<0.05);治疗前两组日常生活能力量表Barthel指数(Barthel指数)、美国国立卫生院卒中量表神经功能缺损(NIHSS)及Fugl-Meyer运动功能量表(FMA)评分比较差异无统计学意义;治疗后Barthel指数、FMA运动评分高于对照组,且NIHSS评分低于对照组(P<0.05);观察组治疗总有效率高于对照组(P<0.05)。结论脑苷肌肽辅助治疗老年脑梗死患者的有效性显著,可改善神经功能缺损程度,提升治疗效果,提高运动功能,值得推广。

Objective To investigate the effectiveness of cerebroside carnosine in the treatment of elderly patients with cerebral infarction.Methods 62 elderly patients with cerebral infarction from May 2017 to June 2018 were enrolled.The patients were divided into observation group and control group according to the time of admission,with 31 cases in each group.The observation group was treated with routine treatment+cerebroside carnosine,the control group was given conventional treatment to compare the therapeutic effects between two groups.Results After treatment,the high/low density lipoprotein cholesterol ratio(LDL-C/HDL-C),hypersensitive c-reactive protein(hs-CRP),procalcitonin(PCT),cystatin C(Cys-C)and homocysteine(Hcy)in the observation group were lower than those in the control group(P<0.05).Barthel index(Barthel index)and the National Institutes of Health Stroke Scale neurological deficit(NIHSS)And the Fugl-Meyer Motor Function Scale(FMA)scores were meaningless.The Barthel index and FMA exercise scores were higher than the control group after treatment,and the NIHSS score was lower than the control group(P<0.05).The total effective rate of treatment was higher than that of the control group(P<0.05).Conclusion The efficacy of cerebroside carnosine in the treatment of elderly patients with cerebral infarction is significant,which can improve the degree of neurological deficit,improve the therapeutic effect and improve the motor function.It is worthy of promotion.