胰腺癌主要危险因素及其作用机制研究

Study on the Main Risk Factors and Mechanism of Pancreatic Cancer

胰腺癌是消化系统中恶性程度极高的肿瘤,其发病机制目前尚不清楚,一般认为是多种因素共同作用的结果。胰腺癌早期无特异性表现,临床诊断较为困难,多数患者确诊时已处于晚期,治疗效果不佳,预后往往较差。因此早期诊断和治疗是改善患者预后的最根本途径,重视胰腺癌的危险因素,进行一级预防意义重大。本文主要对胰腺癌的主要危险因素及其在胰腺癌发病机制中的作用进行综述,旨在为临床预防胰腺癌提供参考。

Pancreatic cancer is a highly malignant tumor in the digestive system.The pathogenesis of pancreatic cancer is currently unknown.Pancreatic cancer has no specific manifestations at an early stage,and clinical diagnosis is difficult.Most patients are in advanced stage when diagnosed,the treatment effect is poor,and the prognosis is often poor.Therefore,early diagnosis and treatment is the most fundamental way to improve the prognosis of patients.It is of great significance to pay attention to the risk factors of pancreatic cancer and carry out primary prevention.This article reviews the main risk factors of pancreatic cancer and its role in the pathogenesis of pancreatic cancer,and aims to provide a reference for clinical prevention of pancreatic cancer.