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冠心病患者血清脂蛋白(a)与纤溶指标水平及相关性研究

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摘要 目的探讨冠心病患者血清脂蛋白(a)[LP(a)]与纤溶指标水平及二者的相关性。方法选取冠心病患者120例为观察组,根据患者疾病类型将其分为不稳定性心绞痛(UAP)组、稳定性心绞痛(SAP)组、陈旧性心肌梗死(OMI)组和急性心肌梗死(AMI)组;选取同期行健康体检的正常人群60例为对照组。均行血清LP(a)、纤维蛋白原(FIB)、D-二聚体(D-D)水平检测,并对其检测结果进行比较。结果与对照组比较,AMI组、UAP组、SAP组、OMI组患者血清LP(a)、D-D、FIB水平均明显升高,且以AMI组与UAP组升高程度更加明显(均P<0.05);经相关性分析显示,冠心病患者血清LP(a)与D-D、FIB均呈正相关(r=0.854、0.878,均P<0.01)。结论冠心病的发生与LP(a)、纤溶功能改变有较大关联。
出处 《实用临床医学(江西)》 CAS 2019年第11期4-5,共2页 Practical Clinical Medicine
基金 中山市卫计局科技基金(2018J058)
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