超声射频信号血管内中膜检测评价食物摄入因素与颈动脉硬化关系的调查研究

Study of quality intima-media thickness in evaluating the relationship between different food intake and carotid atherosclerosis

目的应用超声射频信号血管内中膜分析技术评估颈动脉内中膜厚度,探讨不同食物摄入对颈动脉硬化的影响。方法选取2018年2~12月在我院行颈动脉超声检查的志愿者866例,根据是否存在颈动脉硬化分为硬化组354例和非硬化组512例。使用超声射频信号血管内中膜分析技术检测颈动脉内-中膜厚度(IMT),比较两组IMT;采用偏相关分析膳食食物摄入与颈动脉硬化的相关性;应用条件Logistic回归分析不同食物摄入量与颈动脉硬化风险关系。结果硬化组颈动脉IMT厚度为829μm(724,981),非硬化组为591μm(531,664),两组比较差异有统计学意义(P<0.05)。蔬菜、水果、奶制品摄入量与颈动脉硬化呈负相关(r=-0.100、-0.198、-0.248,均P<0.05),而禽畜类摄入量与颈动脉硬化呈正相关(r=0.278,P<0.05)。校正混杂因素后,蔬菜、水果类摄入量不足及禽畜类摄入过多将增加颈动脉硬化风险(OR=1.93、2.03、3.72,均P<0.05)。结论应用超声射频信号血管内中膜分析技术可以更精准评估颈动脉内中膜厚度;合理指导食物摄入,避免颈动脉硬化的风险。

ObjectiveTo explore the value of quality intima-media thickness(QIMT)in evaluating the relationship between food intake and carotid atherosclerosis.MethodsA total of 866 volunteers in our hospital from February to December2018 were enrolled in and divided into two groups,including carotid atherosclerosis group 354 cases and non-atherosclerosis group 512 cases.QIMT technique was used to evaluate the carotid intima-media thickness(IMT),and the results of two groups was compared.Partial correlation was used to analyze the correlation between food components and carotid sclerosis,conditional Logistic regression analysis was used to compare the differences in carotid sclerosis risk between different food intakes.ResultsThe IMT in the carotid atherosclerosis group was 829μm(724,981),and the non-atherosclerosis group was591μm(531,664).The thickness of intima between two groups were signicantly different(P<0.05).The intake of vegetables,fruits,and dairy products was negatively correlated with carotid sclerosis(r=-0.100,-0.198,-0.248,all P<0.05),while the intake of poultry and livestock was positively correlated with carotid sclerosis(r=0.278,P<0.05).After adjusting for confounding factors,insufficient intake of vegetables and fruits and excessive intake of poultry and livestock will increase the risk of carotid sclerosis(OR=1.93,2.03,3.72,all P<0.05).ConclusionQIMT technique can more accurately assess the carotid artery-media membrane thickness,thus guide food intake to avoid the risk of carotid arteriosclerosis.