子宫肌瘤微创手术中右美托咪定给药方式对比

Comparison of Dexmedetomidine Administration Methods in Minimally Invasive Surgery for Uterine Fibroids

目的探究右美托咪定不同给药方式在子宫肌瘤微创手术患者中的应用效果对比。方法选取于本院诊治的子宫肌瘤并进行微创手术的患者,分为两组,每组30例。第一组,单次注射组(SI组);第二组,持续注射组(CI组)。SI组和CI组患者在一般资料上差异无统计学意义。通过分析SI组和CI组患者心率、平均动脉压、应激反应相关指标、继发效应的差异性来探究右美托咪定不同给药方式在子宫肌瘤微创手术患者中的应用效果对比。结果在T0时间点,SI组和CI组患者心率、平均动脉压指标数据相近(P>0.05),在T1、T2时间点,SI组患者平均动脉压、心率等指标比CI组优良(P<0.05)。麻醉前,SI组和CI组患者应激反应相关指标数值相差较小(P>0.05),术后,SI组患者应激反应相关指标比CI组优良(P<0.05)。两组患者继发效应发生情况差异无统计学意义(P>0.05)。结论右美托咪定在手术过程中麻醉效果显著,但单次注射的方法对患者的麻醉效果更佳,继发效应更少。

Objective To investigate the effect of different dexmedetomidine administration methods in patients with minimally invasive surgery for uterine fibroids.Methods Patients who underwent minimally invasive surgery for uterine fibroids diagnosed and treated in our hospital were divided into two groups,30 in each group.The first group,single injection group(SI group);the second group,continuous injection group(CI group).There were no differences in general information between the SI group and the CI group.To compare the effects of different dexmedetomidine administration methods in patients with minimally invasive surgery of uterine fibroids by analyzing the differences in heart rate,mean arterial pressure,stress-related indicators and secondary effects in SI and CI groups.Results At the T0 time point,the heart rate and mean arterial pressure data were similar between the SI group and the CI group(P>0.05).At the T1 and T2 time points,the average arterial pressure and heart rate of the SI group were better than those of the CI group(P<0.05).Before anesthesia,the values of stress response related indexes in SI group and CI group were small(P>0.05).After operation,the stress response index of SI group was better than that of CI group(P<0.05).There was no significant difference in secondary effect between the two groups(P>0.05).Conclusion Dexmedetomidine has a significant anesthetic effect during the operation,but the single injection method has better anesthesia effect and less secondary effects.