阴阜颗粒细胞瘤1例

A Case of Granular Cell Tumor of the Mons Pubis

患者女,48岁,阴阜结节伴疼痛5年余,手术切除后2年。阴阜右侧一黄豆大小结节,质硬,触之有刺痛。皮损组织病理示:肿瘤细胞成片状条索状分布,间隔可见胶原纤维束,肿瘤细胞体积较大,胞质充满粗大的嗜酸性颗粒,核位于中央。免疫组织化学染色:S-100(+)、NSE(+)、Vimentin(+)、CD68(+)、Ki-67(1%+)。诊断:阴阜颗粒细胞瘤。予外科手术完整切除肿物治疗。

A 48-year-old female patient presented a nodule on her mons pubis accompanied by pain for five years.Two years after surgery,she returned to our department for a follow-up visit.Histopathological findings showed that the tumor cells were distributed in flakes or cords with collagen fiber bundles in between.The tumor cells were large with coarse granular cytoplasm and nuclei located in the middle.Immunohistochemical showed S-100(+),NSE(+),Vimentin(+),CD68(+),and Ki-67(1%+).Granular cell tumor was diagnosed and treated by surgical resection.