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9048例妇科门诊就诊女性15种高危宫颈人乳头瘤病毒感染分析 被引量:2

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摘要 目的分析解放军第990医院妇科门诊女性患者15种高危型人乳头瘤病毒(HR-HPV)的感染情况,以了解该地区妇科就诊女性HR-HPV感染特点。方法采用荧光PCR技术对2016年—2018年该院妇科门诊就诊并筛查15种HR-HPV的9048例女性患者进行检测。结果9048例就诊女性中,HR-HPV阳性共1062例,总阳性检出率11.74%,20~39岁及50~69岁年龄段HR-HPV阳性检出率较高,其中单一亚型感染863例,双重感染160例,三重感染39例。2016年—2018年,各年总阳性检出率分别为10.50%、11.60%、13.00%,数值呈现略微上升趋势,2016年—2018年总阳性检出率比较差别有统计学意义。单一感染常见亚型依次为:16、58、52、51、39,双重感染常见亚型依次为:16、58、59、52、51,三重感染常见亚型依次为:16、56、51、35、18(56),三年未检测出82型,双重及三重感染病例中未检测出68型。结论2016年—2018年该地区妇科门诊患者HR-HPV阳性检出率为11.74%,近年阳性检出率有上升趋势;应重视20~39岁及50~69岁年龄段妇科门诊女性HR-HPV预防及管理;该地区常见HR-HPV亚型依次是:16、58、52、51、39,可为当地HPV疫苗覆盖面提供依据。
机构地区 解放军第 青岛大学
出处 《实用医药杂志》 2020年第3期223-226,共4页 Practical Journal of Medicine & Pharmacy
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