北京市学生男男性行为者HIV和梅毒感染状况

Prevalence of HIV and syphilis among male students who have sex with men (MSM) in Beijing

目的了解北京市学生男男性行为者(MSM)艾滋病病毒(HIV)和梅毒感染状况。方法于2011年7月至2014年12月,在北京市招募学生MSM开展队列研究。本研究采用自填式问卷调查方式,收集研究对象的社会人口学和性行为特征等资料,进行HIV和梅毒检测。统计分析使用SPSS 13.0,影响因素用Logistic回归进行单因素和多因素分析。结果本研究基线共招募143名学生MSM,其中HIV感染率为3.5%(5名),梅毒感染率为4.2%(6名)。多因素Logistic回归结果显示,与HIV感染有统计学意义的因素有:是少数民族[比值比(OR)=10.39,95%可信区间(CI):1.22~88.68];首次与男性发生插入性性行为年龄在18岁及以上(OR=0.08,95%CI:0.01~0.56)。138名学生MSM进入随访,随访截止到2015年7月,队列保持率为79.7%(110名),HIV和梅毒螺旋体血清抗体阳转率分别为0.87/100人年(95%CI:0.15~4.71),7.81/100人年(95%CI:2.41~12.10)。结论北京市学生MSM中HIV/梅毒感染疫情严重,应该引起重视。通过加强青少年时期HIV相关知识的宣传以及性方面的教育,让其认识到高危性行为与HIV感染的相关性。

Objective To know the prevalence of HIV and syphilis among male students having sex with men(MSM) in Beijing. Methods MSM students were recruited in Beijing from July, 2011 to December, 2014. The data about their demographic features and sexual behaviors were collected by a self-administered questionnaire. And blood was sampled to detect HIV and syphilis antibody. The data were then analyzed by SPSS 13.0. The related factors were analyzed by univariate and multivariate logistic regression analysis. Results The prevalence was 3.5%(5/143)for HIV and 4.2%(6/143)for syphilis at the baseline of 143 MSM students. Multivariate logistic regression analysis showed that the following factors were statistically significant with HIV infection: ethnic minorities(OR 10.39,95% CI=1.22-88.68), and the age of 18 years or more at the first homosexual behaviors(OR 0.08,95% CI=0.01-0.56). Of the 138 MSM students followed up until July 2015, the cohort retention rate was 79.7%(110/138). The seroconversion rates were 0.87 per 100 person years(95% CI=0.15-4.71)for HIV antibody and 7.81 per 100 person years(95% CI=2.41-12.10)for syphilis antibody. Conclusion The epidemics of HIV and syphilis are serious among male students who have sex with men in Beijing. More attention should be paid to MSM students to strengthen the publicity of HIV related knowledge and sexual health during the adolescent period, and make them understand the association between high risk sexual behavior and HIV infection.