肾移植术后妇女妊娠期的药物治疗

Medication therapy for pregnant patients after kidney transplantation

肾移植后的女性生育能力通常会恢复,但肾移植术后的妊娠期妇女出现妊娠并发症的风险增加,而有些肾移植术后用药可能会受妊娠影响需要调整剂量,甚至某些肾移植术后用药可能会影响胎儿,增加胎儿早产、致畸等不良结局的风险。本文针对肾移植术后妊娠期妇女免疫抑制剂的选择以及妊娠并发症药物治疗的合理应用进行综述,以期对该类人群的临床用药提供参考。

Despite fertility will be recovered after renal transplantation,compare with the general population,the risk of pregnancy complications increases.Therapeutic dosage adjustment and the medication may affect the fetus for pregnancy patient after kidney transplantation,and will increase the risk of adverse outcomes such as premature and congenital abnormalities.In order to provide a reference for the use of drugs in pregnant woman after transplantation,this review summarized the rational use of drug in immunosuppressive therapy and the treatment of various associated diseases that may occur in the targeted people.