具有多种表现的蕈样肉芽肿一例

Mycosis fungoides with multiple manifestations:a case report

患者,男,80岁。手足反复出现多种皮损伴瘙痒、疼痛4年,加重1年。皮肤活检和组织病理示:表皮内及真皮浅层血管周围灶状淋巴样细胞浸润。免疫组化示:CD3(+)、CD4(+)、CD5(-)、CD7(+)、CD8(+)、CD20(+),Ki67(10%)。诊断:蕈样肉芽肿。予以抗组胺药物、糖皮质激素药膏、窄谱中波紫外线照射治疗,随访。

A 80-year-old man presented with various lesions on his hands and feet with itching and pain for 4 years,aggravating for 1 year.Skin biopsy showed that a crumb mass of lymphocytes were seen in the dermis.Immunohistochemistry demonstrated positive for CD3,CD4,CD7,CD8,CD20,negative for CD5,and Ki-67 presented a level proliferation index of 10%.The diagnosis of mycosis fungoides was made.The patient was treated with antihistamine,topical glucocorticoid and narrow-spectrum UVB.The patient is under follow-up.