恶性肿瘤化疗患者两种中心静脉置管方式疗效及安全性比较

Comparison of Efficacy and Safety of Two Central Venous Catheterization Methods in Patients with Malignant Tumor Chemotherapy

目的探讨恶性肿瘤化疗患者两种中心静脉置管方式疗效及安全性。方法方便选取2016年10月—2017年11月该院收诊的70例恶性肿瘤化疗患者,分层随机法分为观察组35例(植入式静脉输液港)与对照组35例(经外周中心静脉置管),比较两组恶性肿瘤化疗患者的各项临床指标。结果治疗后,观察组导管维护时长(3.19±0.47)min、Kolcaba评分(73.61±5.39)分、KPS评分(87.18±9.06)分、ADL评分(77.24±8.07)分、置管6个月导管留置率(82.56%)、置管1年导管留置率(34.29%)、不良事件发生率(5.71%)均优于对照组且差异有统计学意义(t=27.297,P=0.000;t=15.704,P=0.000;t=11.004,P=0.000;t=6.271,P=0.000;χ^2=20.902,P=0.000;χ^2=14.483,P=0.001;χ^2=5.285,P=0.016)。结论植入式静脉输液港可有效提高恶性肿瘤化疗患者预后质量与安全性,值得推广使用。

Objective To investigate the efficacy and safety of two central venous catheterization methods for chemotherapy patients with malignant tumors.Methods Seventy patients with malignant tumor chemotherapy admitted to the hospital from October 2016 to November 2017 were enrolled.The stratified randomized method was divided into observation group 35 cases(implanted intravenous infusion port)and control group 35 cases(via peripheral area central venous catheterization),compare the clinical indicators of two groups of malignant tumor chemotherapy patients.Results After treatment,the catheter maintenance duration(3.19±0.47)min,Kolcaba score(73.61±5.39)points,KPS score(87.18±9.06)points,ADL score(77.24±8.07)points,and catheter placement for 6 months were observed in the observation group(82.56%),catheter placement rate(34.29%)and adverse event rate(5.71%)were superior to the control group(t=27.297,P=0.000;t=15.704,P=0.000;t=11.004,P=0.000;t=6.271,P=0.000;χ^2=20.902,P=0.000;χ^2=14.483,P=0.001;χ^2=5.285,P=0.016).Conclusion Implanted intravenous infusion port can effectively improve the quality and safety of prognosis in patients with malignant tumor chemotherapy,and it is worthy of popularization.