2017—2018年某医院骨科和普外科围术期患者解热镇痛药物利用分析

Analysis of antipyretic and analgesic drug use on orthopedics and general surgery patients in a hospital from 2017 to 2018

目的调查某医院2017—2018年镇痛药物的使用情况,为镇痛药物的规范化管理和临床合理用药提供参考。方法采用回顾性分析方法,调取某医疗机构2017—2018年镇痛药物处方信息进行药物利用研究(DUR)。包括金额排序分析、序号比(B/A)分析、DDDs分析、DDC分析、DUI等指标,从宏观上分析研究医疗机构2年来镇痛药物利用的合理性。结果该医疗机构2017—2018年药品金额排在前3位的分别是氟比洛芬、丙帕他莫和氯诺昔康;DDDs前3位的分别是氯诺昔康、氟比洛芬和丙帕他莫,其DDDs值占全部研究药物DDDs总和的93.55%;氯诺昔康的序号比值B/A最大,最小的为氟比洛芬;大多数镇痛药物DUI值接近1,其中最大的为氯诺昔康,约为1.3,提示用药剂量偏大。结论该医疗机构2017—2018年镇痛药物应用基本合理,但也存在一些不合理的用药,在优化镇痛药物利用方面仍有潜力,需进一步改进。

Objective To investigate the use of Analgesics in a hospital from 2017 to 2018 so as to provide reference for standard management and clinic rational use of analgesic drugs.Methods A retrospective analysis method was used to retrieve the prescription information of analgesic drugs for a medical institution from 2017 to 2018 for drug utilization research(DUR)including the amount of sort analysis,serial number ratio(B/A)analysis,DDDs analysis,DUI and other indicators.The rationality analysis of the use of analgesic drugs in this medical institution in the past two years was analyzed from the macro perspective.Results The top three drugs in the medical institution from 2017 to 2018 were flurbiprofen,propacetamol and lornoxicam;the top three DDDs were lornoxicam,flurbiprofen,and propaceta,and its DDDs accounted for 93.55%of the total DDDs of all study drugs;lornoxicam′s serial number ratio B/A was the largest,and the smallest was flurbiprofen;most analgesic drugs DUI value was close to 1,among them the largest value was about 1.3 for lornoxicam,indicating that the dosage was a bit large.Conclusion The application of analgesic drugs in this medical institution from 2017 to 2018 is basically reasonable,but there are also some unreasonable drugs.There is still potential in optimizing the utilization of analgesic drugs,which needs further improvement.