多巴胺联合酚妥拉明辅助治疗小儿重症肺炎疗效临床研究

Clinical study of the curative effect of dopamine combined with phentolamine in the adjuvant treatment of severe pneumonia in children

目的:分析酚妥拉明与多巴胺治疗小儿重症肺炎的临床效果.方法:2018年2月-2019年2月收治小儿重症肺炎患者60例,随机分为两组,各30例.对照组接受常规治疗;观察组接受多巴胺和酚妥拉明联合治疗.比较两组治疗效果.结果:观察组肺炎控制率高于对照组,临床症状消除时间及平均住院时间均低于对照组,治疗后动脉血二氧化碳分压、血氧分压、血氧饱和度及血浆黏度等指标水平均优于对照组,差异均有统计学意义(P<0.05).结论:采用酚妥拉明和多巴胺联合治疗小儿重症肺炎,可在缩减患儿各项临床症状消除时间的同时提升肺炎控制率,临床治疗效果显著.

Objective:To analyze the clinical effect of phentolamine and dopamine in the treatment of severe pneumonia in children.Methods:From February 2018 to February 2019,60 children with severe pneumonia were enrolled,they were randomly divided into two groups with 30 cases in each group.The control group received routine treatment;The observation group received combined treatment of dopamine and phentolamine.The therapeutic effects between the two groups were compared.Results:The control rate of pneumonia in the observation group was higher than in the control group,the time of clinical symptoms eliminating and the average hospitalization time were lower than in the control group,after treatment,the indexes of carbon dioxide partial pressure in arterial blood,partial pressure of blood oxygen,degree of blood oxygen saturation and plasma viscosity were better than those of the control group,the differences were statistically significant(P<0.05).Conclusion:The combination of phenytolamine and dopamine in the treatment of severe pneumonia in children can reduce the time of elimination of clinical symptoms and improve the control rate of pneumonia,the clinical treatment effect is remarkable.