西安地区健康成人尿液有形成分参考区间的建立

Establishment of A Reference Interval for the Formation of Urine in Healthy Adults in Xi’an

目的建立西安地区健康成人尿液有形成分参考区间。方法参照临床实验室检验项目参考区间制定的行业标准WS/T 402~2012,组织西安地区6家医院(西京医院,唐都医院,西安交通大学第一附属医院,西安交通大学第二附属医院,陕西省人民医院,西北妇女儿童医院)应用尿液有形成分分析仪Sysmex UF1000i检测健康查体人员1487例(男性935例,女性552例)、孕妇体检人员随机中段尿液标本247例,共计1734例,检测项目包含尿液红细胞(RBC)、白细胞(WBC)、上皮细胞(EC)、细菌(BACT)和管型(CAST)等参数。结果西安地区尿液有形成分参考区间(单位:个/μl):男性:RBC:0~9.4,WBC:0~9.5,EC:0~4.6,CAST:0~1.68和BACT:0~53.9;女性:RBC:0~20.2,WBC:0~15.9,EC:0~25.8,CAST:0~1.26和BACT:0~722.0;孕妇:RBC:0~37.4,WBC:0~40.5,EC:0~55.7,CAST:0~3.59和BACT:0~2201.2;其中,尿液有形成分RBC,WBC,EC,BACT和CAST男性、女性、孕妇间统计学均有显著性差异(P<0.05)。结论该次实验建立了西安地区健康成人尿液有形成分参考区间,为西安地区各医院尿液参考区间临床应用提供参考依据。

Objective Establish a reference interval for the formation of healthy adult urine in Xi’an area. Methods Refer to the industry standard WS/T 402-2012 developed by the reference section of the clinical laboratory test project to organize 6 hospitals in Xi’an( Xijing Hospital,Tangdu Hospital,the First Affiliated Hospital of Xi’an Jiaotong University,the Second Affiliated Hospital of Xi’an Jiaotong University,Shaanxi Provincial People’s Hospital,Northwest Women’s and Children’s Hospital) Sysmex UF1000 i was used to detect 1 487 cases of healthy physical examination personnel( 935 males and 552 females),and 247 randomized mid-section urine samples of pregnant women,totaling 1 734 cases. It includes test parameters such as urine red blood cells( RBC),white blood cells( WBC),epithelial cells( EC),bacteria( BACT) and cast( CAST). Results Xi’an area urine formation reference interval( unit:/μl) : male: RBC: 0 ~ 9. 4,WBC: 0 ~ 9. 5,EC:0 ~ 4. 6,CAST: 0 ~ 1. 68,BACT: 0 ~ 53. 9,female : RBC: 0 ~ 20. 2,WBC: 0 ~ 15. 9,EC: 0 ~ 25. 8,CAST: 0 ~ 1. 26 and BACT: 0 ~ 722. 0,pregnant women: RBC: 0 ~ 37. 4,WBC: 0 ~ 40. 5,EC: 0 ~ 55. 7,CAST: 0 ~ 3. 59,BACT: 0 ~ 2 201.2,urine had a significant difference in RBC,WBC,EC,BACT and CAST male,female,and maternal( P < 0. 05). conclusion This experiment established a reference interval for the formation of urine in healthy adults in Xi’an,which provided a reference for the clinical application of urine reference intervals in hospitals in Xi’an.