阿司匹林、氯吡格雷结合针灸治疗急性脑梗死的临床效果分析

Clinical Analysis of Aspirin and Clopidogrel Combined with Acupuncture for Acute Cerebral Infarction

目的探讨阿司匹林、氯吡格雷、针灸联合应用于急性脑梗死治疗价值。方法以该院2018年10月—2019年7月内收治的80例急性脑梗死患者作为该次研究对象,利用随机数字表法将其分为研究组(n=40)与对照组(n=40)。对照组在常规治疗基础上加用阿司匹林、针灸,研究组在常规治疗基础上加用阿司匹林、氯吡格雷、针灸,记录两组治疗效果、治疗前后运动能力及生活能力变化情况、治疗前后生活质量改善效果、不良反应发生情况。结果研究组临床总有效率(95.00%)高于对照组(80.00%),数据对比差异有统计学意义(χ^2=4.114,P=0.043);两组治疗前Fugl-Meyer量表、Barthel指数评分情况对比均差异无统计学意义(P>0.05),治疗后研究组Fugl-Meyer量表、Barthel指数评分较之前提高幅度优于对照组,组内、组间数据对比均差异有统计学意义(P<0.05);两组治疗前WHOQOL-100量表评分结果对比差异无统计学意义(P>0.05),治疗后研究组WHOQOL-100量表较之前评分结果提高幅度优于对照组,差异有统计学意义(t=8.269,P<0.05);两组治疗期间各项药物相关不良反应发生情况对比差异无统计学意义(P>0.05)。结论应用阿司匹林、氯吡格雷、针灸联合治疗急性脑梗死有效性及安全性均较优。

Objective To explore the therapeutic value of aspirin,clopidogrel and acupuncture in the treatment of acute cerebral infarction.Methods Eighty patients with acute cerebral infarction from were enrolled in this study October 2018-July 2019.They were randomly divided into study group(n=40)and control group(n=40).In the control group,aspirin and acupuncture were added on the basis of routine treatment.The study group added aspirin,clopidogrel and acupuncture on the basis of routine treatment.The therapeutic effects of the two groups,the changes of exercise capacity and living ability before and after treatment,and the quality of life improvement,and the occurrence of adverse reactions before and after treatment were recorded.Results The total effective rate of the study group(95.00%)was higher than that of the control group(80.00%).The difference in data comparison was statistically significant(χ^2=4.114,P=0.043).The Fugl-Meyer scale and Barthel index scores before treatment,the difference was not statistically significant(P>0.05).After treatment,the Fugl-Meyer scale and Barthel index scores of the study group were better than those of the control group.There were statistically significant differences in intra-group and inter-group data(P<0.05).The scores of the WHOQOL-100 scale before treatment were compared with the difference was not statistically significant(P>0.05).After treatment,the WHOQOL-100 scale of the study group was better than the control group the difference was statistically significant(t=8.269,P<0.05).The incidence of drug-related adverse reactions during the treatment period,the difference was not statistically significant(P>0.05).Conclusion The efficacy and safety of aspirin,clopidogrel and acupuncture combined with acute cerebral infarction are superior.