胃镜治疗消化性溃疡合并急性上消化道出血的临床效果分析

Clinical Analysis of Gastroscope in the Treatment of Peptic Ulcer Complicated with Acute Upper Gastrointestinal Hemorrhage

目的探讨对消化性溃疡伴有急性上消化道出血患者给予胃镜治疗的可行性。方法选择该院2017年3月—2019年4月收治的140例消化性溃疡伴有急性上消化道出血患者作为实验对象;数字奇偶法分组后探究每组选取的合并症治疗方法;比照组(70例):选取三联疗法展开合并症治疗;实验组(70例):选取三联疗法+胃镜展开合并症治疗;最终就组间疗效、不良事件发生率以及再出血发生率展开对比。结果实验组消化性溃疡伴有急性上消化道出血患者治疗总有效率(98.57%)高于比照组(84.29%)明显,差异有统计学意义(χ^2=9.115,P<0.05);实验组四肢乏力患者1例,恶心呕吐患者1例,无腹胀患者,总发生率为2.86%;比照组四肢乏力患者4例,恶心呕吐患者4例,腹胀患者3例,总发生率为15.71%;不良事件发生率(2.86%)低于比照组(15.71%)明显,差异有统计学意义(χ^2=6.869,P<0.05);再出血发生率(1.43%)低于比照组(11.43%)明显,差异有统计学意义(χ^2=5.818,P<0.05)。结论消化性溃疡伴有急性上消化道出血患者于临床在接受三联疗法治疗基础上,配合接受胃镜治疗,利于患者治疗效果的提高、不良事件发生率降低以及再出血事件的减少,最终对于消化性溃疡伴有急性上消化道出血的康复进程缩短,奠定基础,进一步说明采用胃镜方法对消化性溃疡伴有上消化道出血患者进行辅助治疗的可行性。

Objective To investigate the feasibility of gastroscopy for patients with peptic ulcer accompanied by acute upper gastrointestinal hemorrhage.Methods A total of 140 patients with peptic ulcer with acute upper gastrointestinal hemorrhage admitted to the hospital from March 2017 to April 2019 were selected as subjects.The digital parity method was used to investigate the treatment options for each group:control group(70 cases):triple therapy was selected for comorbidity treatment;experimental group(70 cases):triple therapy plus gastroscope complication was selected;finally,the effect of group,adverse event rate and incidence of rebleeding were compared.Results The total effective rate of the treatment group with peptic ulcer associated with acute upper gastrointestinal hemorrhage was 98.57%higher than that of the control group(84.29%),the difference was statistically significant(χ^2=9.115,P<0.05).One patient with limb weakness in the experimental group,One patient with nausea and vomiting had no bloating,the total incidence was 2.86%;4 patients with limb weakness in the comparison group,4 patients with nausea and vomiting,and 3 patients with abdominal distension,the total incidence was 15.71%;The incidence of adverse events(2.86%)was significantly lower than that of the control group(15.71%),the difference was statistically significant(χ^2=6.869,P<0.05);the incidence of rebleeding(1.43%)was significantly lower than that of the control group(11.43%),the difference was statistically significant(χ^2=5.818,P<0.05).Conclusion Patients with peptic ulcer associated with acute upper gastrointestinal hemorrhage are treated with triple therapy on the basis of clinical treatment,which is beneficial to the improvement of treatment effect,reduction of adverse event rate and reduction of rebleeding event.The healing process of ulcers with acute upper gastrointestinal hemorrhage is shortened,which lays the foundation and further demonstrates the feasibility of using gastroscopic methods to assist patients with peptic ulcer with upper gastrointestinal bleeding.