江苏省海门市1999-2016年成年女性乳腺癌发病及死亡趋势分析

Analysis on incidence and death trend of breast cancer in adult women from 1999 to 2016 in Haimen,Jiangsu Province

目的分析海门市1999-2016年成年女性乳腺癌发病及死亡率情况。方法利用海门市肿瘤登记报告系统中1999-2016年女性乳腺癌患者的发病及死亡资料,计算粗发病率、粗死亡率、标化率、年龄别率、变化百分比(percent change,PC)和年度变化百分比(annual percentage change,APC)等指标。结果海门市1999-2016年成年女性乳腺癌新发病例2 977人,粗发病率、中标发病率分别为39.29/10万、20.65/10万;APC分别为5.87%、4.71%。因乳腺癌死亡病例938人,粗死亡率、中标死亡率分别为12.38/10万、6.07/10万;APC分别为3.87%、2.43%。乳腺癌年龄别发病率随年龄递增,30~岁发病迅速攀升,发病高峰出现在55~岁(65.05/10万)及70~岁(60.77/10万);乳腺癌年龄别死亡率随年龄呈缓慢递增,直至80岁出现死亡高峰(29.68/10万)。结论海门市乳腺癌发病率和死亡率总体呈现逐年上升趋势,且随年龄增长而递增。世标发病率及世标死亡率均高于全省及全国水平。应加强本地区乳腺癌的防治工作。

Objective To analyze the incidence and mortality of female breast cancer from 1999 to 2016 in Haimen City.Methods Data of female breast cancer from 1999 to 2016 in the Haimen Tumor Registry Reporting System were used to calculate the crude incidence and mortality,standardized incidence and mortality,age-specific incidence and mortality,percentage change of rate(PC)and annual percentage change of rate(APC).Results There were 2977 cases from 1999 to 2016.The crude incidence and age-standardized incidence by Chinese standard population were 39.29/100000 and 20.65/100000,respectively;APC were 5.87%and 4.71%,respectively.There were 938 deaths,the crude mortality and standardized mortality by Chinese standard population were 12.38/100000 and 6.07/100000,respectively;APC were 3.87%and 2.43%,respectively.The incidence increased with age,with a sharp increase occuring in 30-years old and two peaks occuring in 55-years old(65.05/100000)and 70-years old(60.77/100000).The mortality gradually increased with age and the peak was at age 80(29.68/100000).Conclusion The incidence and mortality of female breast cancer in Haimen City had a upward trend with year and age.The age-standardized incidence and mortality by world standard population were higher than provincial and national levels.The work for prevention and control of female breast cancer in this region should be strengthened.