四妙勇安汤在老年性疾病中的应用

Application of Simiaoyong'an Decoction in Geriatric Diseases

四妙勇安汤是中医经典名方,由金银花、玄参、当归、甘草四味药物组成,具有清热解毒、活血通脉的作用,该方在古籍记载中为治疗痈疽之专剂,其原方或加减方能改善老年性疾病患者“虚、热、毒、瘀”互结的状态。现代药理学研究表明,该方具有较好的抗炎、保护血管和改善微循环、降低血脂水平、稳定斑块等作用。临床研究证实,该方现已广泛应用于老年性心血管疾病、脑及神经疾病、呼吸系统疾病、感染性及自身免疫性炎症等本虚标实的各种病症,临床疗效显著。本研究对四妙勇安汤治疗老年病的机理、药理作用、临床应用做一综述,本研究认为,四妙勇安汤现代临床应用已远超出其古代运用范围,其治疗各类老年疾病的机制可能与改善慢性炎症和维持微循环稳态密切相关。

Simiaoyong'an decoction is a classic Chinese medicine prescription,which consists of honeysuckle,scrophulariaceae,angelica and licorice.It has the functions of clearing away heat and detoxifying,and promoting blood circulation.This is a special prescription for treating ulcer in ancient books,and can improve the status of“virtual,heat,poison,and phlegm”of geriatric patients.Pharmacology reseach has shown that the prescription has good effects on anti-inflammatory,protecting blood vessels,improving microcirculation,reducing blood lipid levels,and stabilizing plaque etc.Simiaoyong'an decoction has been widely used in geriatric cardiovascular diseases,brain and neurological diseases,respiratory diseases,infectious inflammation,autoimmune inflammation and other diseases,and the clinical effect is remarkable.This article reviews the mechanism on the treatment of geriatric disease,pharmacologic action,clinical application of simiaoyong'an decoction.The research group believes that the modern clinical application of simiaoyong'an decoction has far exceeded its ancient application range.The mechanism of its treatment of various geriatric diseases may be closely related to the improvement of chronic inflammation and microcirculation steady state.