非糜烂性食管炎和内脏高敏感研究新进展

The Current Resaerch on Nonerosive Reflux Disease and Visceral Hypersensitivity

胃食管反流病(GERD)是一种常见的消化道疾病,我国GERD发病率逐年增高。既往研究将GERD分为反流性食管炎(RE),非反流性食管炎(NERD),Barrett食管。抗酸药物在针对GERD的治疗方面极为重要,但对部分GERD患者抗酸药物效果微弱。NERD,Barrett食管,RE的发病机制并不完全相同,近年来内脏超敏感在NERD发病机制的研究越来越受到重视,本文将对相关研究进行综述。

Gastroesophageal reflux disease(GERD)is a common disease.With the increasing of obese population,the incidence of GERD increases year by year.Previous studies have classified GERD into reflux esophagitis RE,non-reflux esophagitis(NERD),Barrett esophagus.Anti-acid drugs are very important in the treatment of GERD but the effect of anti-acid drugs on some GERD patients is weak.The pathogenesis of NERD,Barrett esophagus and RE is not exactly the same.In recent years,more and more attention has been paid to the study of visceral hypersensitivity in the pathogenesis of NERD.This paper will summarize the related research.