养阴益气活血汤对慢性心力衰竭患者心功能及生活质量的影响

Effect of Yangyin Yiqi Huoxue Tang on Heart Function and Quality of Life in Patients with Chronic Heart Failure

目的:研究养阴益气活血汤对慢性心力衰竭患者心功能和生活质量的影响。方法:将慢性心力衰竭患者86例随机分为2组。对照组采用常规西药治疗,观察组联合养阴益气活血汤治疗。观察比较2组左心室射血分数(LVEF)、左心室收缩末期内径(LVESD)、左心室舒张末期内径(LVEDD)、生活质量评分、中医证候积分、疗效和不良反应。结果:治疗后,2组LVEF升高,LVEDD、LVESD降低,且观察组LVEF高于对照组,LVEDD、LVESD低于对照组,差异有统计学意义(P<0.05)。治疗后,2组中医证候积分、生活质量评分均降低,且观察组中医证候积分、生活质量评分低于对照组,差异有统计学意义(P<0.05)。观察组总有效率为93.02%,对照组总有效率为76.74%,观察组总有效率高于对照组(P<0.05)。结论:养阴益气活血汤治疗慢性心力衰竭,能显著改善患者心功能,提高生活质量,安全可靠。

Objective:To study the effect of Yangyin Yiqi Huoxue tang on the heart function and quality of life in patients with chronic heart failure. Methods:A total of 86 cases of patients with chronic heart failure were randomly divided into two groups. The control group was treated with routine western medicine, and the observation group was additionally treated with Yangyin Yiqi Huoxue tang based on the treatment of the control group. The left ventricular ejection fraction(LVEF), left ventricular end-systolic dimension(LVESD), left ventricular end diastolic diameter(LVEDD), scores of quality of life and Chinese medicine syndrome, curative effect and adverse reactions in the two groups were observed and compared.Results:After treatment, LVEF in the two groups was increased, and the one in the observation group was higher than that in the control group;LVEDD and LVESD in the two groups were decreased, and the ones in the observation group were higher than those in the control group, the difference being significant(P<0.05). After treatment, the scores of Chinese medicine syndrome and quality of life in the two groups were decreased, and the scores in the observation group were lower than those in the control group(P<0.05). The total effective rate was 93.02% in the observation group, higher than that of76.74% in the control group(P<0.05). Conclusion:Yangyin Yiqi Huoxue tang in treating chronic heart failure can significantly improve the heart function and quality of life, which is safe and reliable.