氦氖激光治疗喀什地区儿童弱视的随机对照研究

Efficacy of helium-neon laser in amblyopia of Kashgar children:A randomized controlled trial

目的:通过随机对照试验,观察氦氖激光在喀什地区弱视儿童中的治疗效果。方法:选取2016年2月至2018年11月期间就诊喀什地区第一人民医院符合纳排标准的弱视儿童,按随机数字表法,分为试验组(氦氖激光+弱视常规治疗组)与对照组(弱视常规治疗组),比较两组的弱视治疗效果。结果:本试验成功纳入弱视儿童111例(177眼),其中试验组61例(97眼),对照组50例(80眼)。与对照组相比,汉族试验组弱视儿童效果明显(P=0.023),维吾尔族试验组弱视儿童未见明显疗效(P=0.481);试验组与对照组在喀什地区不同年龄、不同弱视程度、不同弱视类型及不同弱视眼数儿童中未见明显差异(P>0.05)。结论:氦氖激光治疗喀什地区弱视儿童作用有限,为避免过度医疗,不建议在南疆地区开展。

Objective:To observe the therapeutic effect of helium-neon laser in amblyopia children in Kashgar by a randomized controlled trial.Methods:Amblyopia children who met eligibility criteria during February 2016 to November 2018 were selected and divided into two groups according to random number table:test group(helium-neon laser+conventional treatment for amblyopia)and control group(conventional treatment for amblyopia).The effects of amblyopia treatment were compared between two groups.Results:One hundred and eleven amblyopic children(177 eyes),including 61 children(97 eyes)of the test group and 50 children(80 eyes)of the control group were included in this study.The effect of helium-neon laser was significant in Han children(P=0.023),but not in Uygur children(P=0.481)in the test group compared with the control group.Conclusion:Helium-neon laser has limited effect in treating children with amblyopia in Kashgar region.To avoid over-treatment,it is not recommended to perform it in southern Xinjiang.