从SARS冠状病毒探讨新型冠状病毒眼途径传播的可能机制

Investiagation of possible mechanism of eye transmission of SARS-CoV-2 based on SARS-CoV

新型冠状病毒(SARS-CoV-2)自2019-12爆发以来,传播速度极快,了解其流行病学特征,尤其是切断传播途径对于控制疾病传播至关重要。在传播途径的研究中,SARS-CoV-2是否通过眼表组织进行传播的问题也引起关注,但目前尚缺乏其通过眼表组织感染的临床确诊病例和实验室证据。最新研究认为SARS-CoV-2与SARS冠状病毒(SARS-CoV)属于同一种属,并且其与SARS-CoV进入细胞的途径是一样的。本文通过回顾SARS-CoV的研究,探讨SARS-CoV-2眼途径传播的可能机制。

SARS-CoV-2 has been spreading rapidly since its outbreak in December 2019.Understanding its epidemiological characteristics,especially cutting off transmission routes,is crucial to controlling the spread of the disease.In the study of transmission pathway,the issue of whether SARS-CoV-2 is transmitted through ocular surface tissue has also aroused concerns,but there are still no clinically confirmed cases and laboratory evidence of its infection through ocular surface tissue.New research suggests that the SARS-CoV-2 belongs to the same genus as SARS coronavirus(SARS-CoV),and that it enters cells in the same way as SARS-CoV.This paper reviews the research on SARS-CoV to investigate the possible mechanism of eye transmission of SARS-CoV-2.