摘要
目的阐述乙型肝炎相关肝癌疾病通过凝血四项指标、肿瘤标志物联合检验的临床应用价值。方法选取2018年7月至2019年7月宜兴市人民医院收治的57例确诊为乙型肝炎相关肝癌疾病的患者为观察组,选择同期收治的57例确诊为良性肝病的患者为对照组,均实施凝血四项、肿瘤标志物检测,比较两组患者各项指标的差异情况。结果观察组患者凝血四项指标中,凝血酶原时间(19.93±2.36)s、凝血活酶时间(49.54±4.77)s、凝血酶时间(24.25±2.88)s均明显高于对照组,而纤维蛋白原值(1.68±0.35)g/L则低于对照组,组间比较差异有统计学意义(P<0.05)。同时,观察组患者肿瘤标志物甲胎蛋白值(99.02±7.46)μg/L、岩藻糖苷酶值(79.66±4.24)U/L则均高于对照组(P<0.05)。结论通过凝血四项指标、肿瘤标志物检验能够有效鉴别肝癌,准确性较高,提倡推广应用。
Objective To expound the clinical application value of combined detection of four indexes of coagulation and tumor markers in hepatitis b related liver cancer diseases.Methods This study is scheduled from July 2018 to July 2019.The subjects selected 57 patients with hepatitis B-related liver cancer diagnosed in our hospital as observation group.57 patients with benign liver disease diagnosed in our hospital during the same period were selected as control group.All patients were tested for four coagulation items and tumor markers,and the differences of each index between groups were compared.Results Among the four indexes of coagulation in the observation group,prothrombin time(19.93±2.36)s,prothrombin time(49.54±4.77)s and thrombin time(24.25±2.88)s were significantly higher than those of the control group,while the fibrin original value(1.68±0.35)g/L was lower than the control group,with significant difference(P<0.05).Meanwhile,the tumor marker alpha-fetoprotein[(99.02±7.46)μg/L],and fucoglycoside enzyme[(79.66±4.24)U/L]in the observation group were all higher than those in the control group(P<0.05).Conclusion The four indexes of coagulation and the detection of tumor markers can effectively differentiate hepatocellular carcinoma with high accuracy and promote its popularization and application.
作者
钱国娟
QIAN Guojuan(Yixing People's Hospital,Yixing,Jiangsu 214200,China)
出处
《大医生》
2019年第18期57-58,共2页
Doctor
关键词
凝血四项指标
肿瘤标志物
乙型肝炎
肝癌
检验
four indicators of coagulation
tumor markers
hepatitis B
hepatocellular carcinoma
testing