摘要
Micro/nano biosensors had rapidly progressed and enabled a verity of applications that were otherwise impossible/challenging with traditional methods.The three key components in micro/nano biosensors consist of(1)the analyte preparation(living cells or biomarker molecules),(2)signal transduction(from bio-signal/event to more readable electronic/optical signal),and(3)signal readout(preferably by integrated instrumentation).A verity of work has been dedicated to each of these three areas.It is now evident that micro/nanotechnology is playing a significant role in the development of cell and molecule biosensors.The performance of biosensors was significantly enhanced by combining the micro/nanostructures,which present unique physical and chemical characteristics due to various effects at these scales.