颅内动脉瘤介入术后脑缺血并发症的相关因素分析

Factors for cerebral ischemia complications after intracranial aneurysm intervention

目的分析诱发颅内动脉瘤介入术后脑缺血并发症的因素。方法回顾性分析本院2010年1月~2018年12月35例颅内动脉瘤介入术后脑缺血并发症的患者的临床资料,记为A组;另回顾性分析同时间段41例颅内动脉瘤介入术后未并发脑缺血并发症的患者的临床资料,记为B组。归纳脑缺血并发症的可能影响因素,对比A组与B组差异,并进行Logistic多元回归分析。结果两组患者性别、年龄、病程时间、动脉瘤位置、糖尿病史、蛛网膜下腔出血病史、脑梗死或短暂性脑缺血发作病史、饮酒史、颅内血管狭窄、治疗策略、支架类型、Raymond分级相比较,差异无统计学意义(P>0.05),高血压病史、吸烟史、动脉瘤直径和最大径相比较,差异有统计学意义(P<0.05);Logistic回归分析结果提示,高血压、吸烟、动脉瘤最大径>10 mm为颅内动脉瘤介入术后脑缺血并发症的独立风险因素(P<0.05)。结论高血压、吸烟、动脉瘤最大径>10 mm为颅内动脉瘤介入术后脑缺血并发症的独立危险因素。

Objective To investigate the independent risk factors for cerebral ischemia complications after intracranial aneurysm intervention.Methods A retrospective analysis was performed for the clinical data of 35 patients who experienced cerebral ischemia complications after intracranial aneurysm intervention in our hospital from January 2010 to December 2018,and these patients were enrolled as group A;a retrospective analysis was also performed for the clinical data of 41 patients who did not experience cerebral ischemia complications after intracranial aneurysm intervention during the same period of time,and these patients were enrolled as group B,and a multivariate logistic regression analysis was performed.Results There were no significant differences between the two groups in sex,age,course of disease,location of aneurysm,history of diabetes,history of subarachnoid hemorrhage,history of cerebral infarction or transient ischemic attack,history of drinking,intracranial vascular stenosis,treatment strategy,stent type,and Raymond classification(P<0.05).The logistic regression analysis showed that hypertension,smoking,and maximum aneurysm diameter>10 mm were independent risk factors for cerebral ischemia complications after intracranial aneurysm intervention(P<0.05).Conclusions Hypertension,smoking,and maximum aneurysm diameter>10 mm are independent risk factors for cerebral ischemia complications after intracranial aneurysm intervention.