聚乙二醇电解质散在40例妇科腹腔镜术前肠道准备中的应用

Application of polyethylene glycol electrolyte powder in intestinal preparation of 40 cases before gynecological laparoscopic operation

目的探讨聚乙二醇电解质散(PGEP)在妇科腹腔镜术前肠道准备中的应用效果.方法选取2019年2月至2019年5月行妇科腹腔镜手术的患者80例,采用随机数字表法分为两组(研究组和对照组各40例).研究组采用肥皂水灌肠联合口服PGEP溶液进行术前肠道准备,对照组采用肥皂水灌肠进行肠道准备,比较两组患者术前血指标及肠道准备的效果.结果两组患者术前血钾、血钠、血红蛋白、红细胞压积、血pH值、低钠血症/低钾血症发生率、术后排气时间及手术医师对患者的肠道准备满意度差异均无统计学意义(P>0.05),两组患者均未发生重度低钠血症、低钾血症或严重并发症;研究组患者血糖[4.90(4.70,5.28)mmol/L vs 5.25(4.83,5.70)mmol/L,z=-2.30,P=0.02]和手术时间[35.00(25.00,50.00)min vs 57.50(41.25,90.00)min,z=-4.01,P<0.001]均低于对照组.结论口服PGEP对妇科腹腔镜术前血钾、血钠、血红蛋白、红细胞压积、血pH值无影响,且能够提高肥皂水肠道准备效果,不影响术后肠蠕动恢复.

Objective To investigate the application of polyethylene glycol electrolyte powder(PGEP)in intestinal preparation before gynecological laparoscopic surgery.Methods A total of 80 patients undergoing laparoscopic gynecological surgery during Feb.2019 and May 2019 were randomly divided into two groups.The study group used soap water enema combined with oral PGEP solution for intestinal preparation before operation,while the control group used soap water enema for intestinal preparation.The blood indexes and intestinal preparation effects of the two groups were compared.Results There were no significant differences between the two groups in blood potassium,blood sodium,hemoglobin,hematocrit,pH value,incidence of hyponatremia/hypokalemia,exhaust time after operation and satisfaction of surgeons with intestinal preparation(P>0.05).No severe hyponatremia,hypokalemia or serious complications occurred.Blood glucose was 4.90(4.70,5.28)mmol/L in the study group and 5.25(4.83,5.70)mmol/L in the con trol group(z=-2.30,P=0.02),and operation time was 35.00(25.00,50.00)min in the study group and 57.50(41.25,90.00)min in the control group(z=-4.01,P<0.001).Conclusion PGEP does not affect blood potassium,blood sodium,hemoglobin,hematocrit and blood pH before gynecological laparoscopic operation.It can improve the intestinal preparation results of soapy water without affecting the recovery of intestinal peristalsis.