人体牙髓干细胞制备、保存及分析鉴定的研究进展

Progress on the Preparation,Preservation and Identification of Human Dental Pulp Stem Cells

人体牙髓干细胞(h DPSCs)是来源于牙髓组织的成体干细胞,属于间充质干细胞,具有分裂增殖、多向分化、再生修复、自我更新功能;h DPSCs在疾病治疗以及组织工程等领域中表现出重要的临床价值和应用前景;hDPSCs的制备、保存及其生物学特性的分析鉴定是实现临床应用的关键和基础。本综述就h DPSCs的体外培养、分离、纯化、保存及其分析鉴定等方面的最新研究进展做一概述。

Human dental pulp stem cells(h DPSCs) are adult stem cells derived from dental pulp.They are mesenchymal stem cells with the potential of division,proliferation,multidifferentiation,regeneration,repair and self-renewal.HDPSCs show important clinical value and application prospect in the field of disease treatment and tissue engineering.The preparation,preservation,analysis and identification of h DPSCs are the key and basis of clinical application.This review summarizes the recent research progress on in vitro culture,isolation,purification,preservation,analysis and identification of h DPSCs.