宫颈癌危险因素的1:1病例对照研究

Case-control Study on Risk Factors of Cervical Cancer

目的 探讨宫颈癌发病的危险因素,为监测和预防提供科学依据.方法 收集2013-2019年西丰县开展的宫颈癌筛查活动检出的宫颈癌患者107例作为病例组,并选择同时期排除宫颈癌诊断的女性107例作为对照组.采用病例对照研究方法,对宫颈癌发病的危险因素进行研究.结果 单因素分析显示,居住地、人乳头瘤病毒(HPV)感染、既往妇科疾病、首次性行为年龄、性行为卫生、初孕年龄、初产年龄、孕次数和产次数是宫颈癌患病的危险因素.多因素分析显示,HPV感染、既往妇科疾病史和产次数是宫颈癌患病的危险因素.结论 宫颈癌发生受多种因素影响,积极控制相关危险因素,加强对高危人群监测,有助于预防宫颈癌发生.

Objective To explore the risk factors of cervical cancer and provide scientific basis for monitoring and prevention.Methods A total of 107 cases of cervical cancer detected by cervical cancer screening activities in Xifeng from 2013 to 2019 were selected as case group,and 107 women who were excluded from cervical cancer at the same time were selected as control group.The risk factors of cervical cancer were evaluated by case-control study.Results Univariate analysis showed that residence,HPV infection,past gynecological diseases,age of first sexual behavior,sexual hygiene,age of first pregnancy,age of first delivery,number of pregnancies and number of deliveries were risk factors for cervical cance匚Multivariate analysis showed that HPV infection,past history of gynecological diseases and the number of deliveries were risk factors for cervical cancer.Conclusion The occurrence of cervical cancer is affected by many factors.Actively control the related risk factors and strengthen the monitoring of high-risk population is helpful to prevent the occurrence of cervical cancer.