摘要
目的 制定精准随访方案,并探讨其在转移性去势抵抗性前列腺癌(mCRPC)患者中的应用效果.方法 将64例mCRPC骨转移患者随机分为干预组和对照组,各32例.对照组采用常规随访,干预组组建多学科协作随访团队,构建骨转移精准随访方案并实施.干预6个月后评价效果.结果 干预组骨相关事件发生率与对照组比较,差异无统计学意义(P>0.05);干预组生活质量各维度得分(除外社会/家庭状况)、疼痛控制满意度显著高于对照组,疼痛强度、疼痛影响及疼痛信念得分显著低于对照组(P<0.05,P<0.01).结论 对mCRPC骨转移患者实施精准随访能显著降低疼痛强度,相对减少骨相关事件发生率,提高患者生活质量.
Objective To develop a precise follow-up protocol and to explore its application effect in patients with metastatic castrated resistant prostate cancer(mCRPC).Methods Sixty-four mCRPC men with bone metastasis were equally randomized into a control group and an intervention group,receiving either conventional follow-ups or precise follow-ups provided by a multidisciplinary team.Effect was evaluated after 6 months of intervention.Results The incidence of bone related adverse events was 9.38%in the intervention group and 28.12%in the control group,but without significant difference between them(P>0.05).The total and dimension scores of quality of life except social/family dimension were significantly higher,whereas pain intensity,pain impact and pain belief were significantly lower,in the intervention group compared with the control group(P<0.05,P<0.01).Conclusion Implementation of precise follow-ups in mCRPC patients with bone metastasis can alleviate pain intensity,reduce bone related adverse events and improve quality of life of patients.
作者
乔够梅
任洁
马丹丹
康亚芬
朱文婷
张继萍
Qiao Goumei;Ren Jie;Ma Dandan;Kang Yafen;Zhu Wenting;Zhang Jiping(Departmentof Urology,The 940th Hospital of PLA,Lanzhou 730050,China)
出处
《护理学杂志》
CSCD
北大核心
2020年第1期9-13,共5页
Journal of Nursing Science
基金
甘肃省自然科学基金项目(1506RJZA311)。
关键词
前列腺癌
去势治疗
骨转移
骨相关事件
疼痛
精准随访
生活质量
AIDET沟通模式
prostate cancer
castration
bone metastasis
bone related adverse event
pain
precise follow-up
quality of life
AIDET communication model