ESM1基因对崇仁麻鸡生长性状的影响

Effect of ESM1 Gene on Growth Traits and Expression in Chongren Partridge Chicken

本研究利用崇仁麻鸡差异性状的重测序结果,筛选与其生长性状相关的SNP、SV和InDel等位点或结构信息并进行大群验证。结果发现:内皮细胞特异性分子-1(ESM1)基因在崇仁麻鸡群体中检测到3个多态位点,对崇仁麻鸡的生长性状有着显著或极显著影响。ESM1基因在崇仁麻鸡的多个组织中均能检测到表达,经软件预测发现,ES-3位点变异可能会引起ESM1蛋白结构或功能的变化。研究结果表明,ESM1基因对崇仁麻鸡的生长性状有一定影响,但能否作为崇仁麻鸡生长性状的分子标记还需要进一步的确认。

In this study,we utilized and tested re-sequencing result related to Chongren partridge chicken growth traits including SNP,SV,InDel and other structural information.The results showed that three polymorphic loci of endothelial cell specific molecule-1(ESM1)gene were verified in Chongren partridge chicken.The association analysis showed that ESM1 gene had significant or extremely significant effects on growth traits of Chongren partridge chicken.ESM1 gene can be detected in many tissues used by fluorescence quantitative PCR.The software Predicted that the ES-3 locus might cause changes in the structure or function of ESM1 Protein.The results showed that ESM1 gene had some effects on growth traits of Chongren Partridge chicken,but whether ESM1 gene could be used as a molecular marker for growth traits in Chongren partridge chicken still needs further confirmation.