血清人绒毛膜促性腺激素、孕酮、雌二醇水平与先兆流产的临床关系探讨

Clinical relationship between the levels of serum human chorionic gonadotropin,Progesterone,estradiol and threatened abortion

目的探讨先兆流产与血清人绒毛膜促性腺激素(HCG)、孕酮(P)、雌二醇(E2)水平的临床关系。方法选取2019年1~7月本院收治的66例先兆流产患者为研究对象,其中33例保胎成功者归入观察组,33例保胎失败者归入对照组,回顾所有患者的临床资料,比较血清HCG、P、E2检测结果。结果在孕3、5、7、9周,观察组比对照组的HCG和P水平高,差异有统计学意义(P<0.05)。在孕5、7、9周,观察组比对照组的E2水平高,差异有统计学意义(P<0.05)。结论先兆流产患者在妊娠早期动态监测HCG、P、E2水平,能预测妊娠结局,同时对早期保胎治疗有着指导作用,值得推广应用。

Objective To explore the clinical relationship between threatened abortion and the levels of serum human chorionic gonadotropin(HCG),progesterone(P)and estradiol(E2).Methods 66 cases of threatened abortion treated in our hospital from January to July 2019 were selected as the research subjects.Among them,33 cases of successfully prevent miscarriage were included in the observation group and 33 cases of miscarriage were included in the control group.The clinical data of all patients were reviewed,and the results of serum HCG,P,E2 were compared and analyzed.Results At the 3 weeks,5 weeks,7 weeks and 9 weeks of pregnancy,the levels of serum HCG and P in the observation group were higher than those in the control group(P<0.05).At 5 weeks,7 weeks and 9 weeks of pregnancy,the E2 level of the observation group was higher than that of the control group,and the difference was statistically significant(P<0.05).Conclusion The dynamic monitoring of serum HCG,P,E2 levels in the early pregnancy of threatened abortion patients can predict the outcome of pregnancy,guide the treatment of prevent miscarriage,and it is worth popularizing.