化积定痛散穴位贴敷对肝癌患者的镇痛研究

Analgesic study of acupoint of huaji dingtong powder on patients with liver cancer

目的探讨肝癌患者应用化积定痛散穴位贴敷治疗的镇痛效果。方法选取2016年2月~2019年6月在我院接受治疗的90例晚期肝癌患者作为研究对象,随机分为三组,各30例,三组患者均给予常规对症支持治疗,其中:治疗组给予化积定痛散外敷加口服盐酸曲马多缓释片;将盐酸曲马多缓释片口服应用于对照一组治疗中;对照二组给予化积定痛散外敷。三组治疗前后记录疼痛评分、生存质量评分等指标,以及记录三组治疗后是否有毒副作用等以评价化积定痛散治疗肝癌疼痛的疗效及意义。结果经治疗后,对照一组以及对照二组患者的VAS评分以及生活质量评分差异无统计学意义(P>0.05);治疗组的患者的VAS分显著低对照一组以及对照二组,差异有统计学意义(P<0.05);治疗组生活质量评分显著高于对照一组以及对照二组,差异有统计学意义(P<0.05);对照二组与治疗组并发症发生率差异无统计学意义(P>0.05);对照一组并发症的发生率显著高于对照二组、治疗组,差异有统计学意义(P<0.05)。结论应用化积定痛散外敷加口服盐酸曲马多缓释片治疗肝癌患者,可有效镇痛,提高患者生活质量,值得在临床上推广应用。

Objective To explore the analgesic effect of acupoint of Huaji Dingtong powder on patients with liver cancer.Methods 90 patients with advanced liver cancer who were treated in our hospital from February 2016 to June 2019 were divided and randomly divided into three groups,with 30 cases in each group.The three groups were given conventional symptomatic and supportive treatment,of which,the treatment group was given Huaji Dingtong powder applied topically plus oral tramadol hydrochloride sustained-release tablets;the control group A was given tramadol hydrochloride sustainedrelease tablets applied orally;the control group B was given Huaji Dingtong powder applied topically.The pain score,quality of life score and other indicators were recorded before and after treatment in the three groups,and whether there were toxic or side effects after treatment in the three groups were recorded to evaluate the efficacy and significance of Huaji Dingtong powder in treating liver cancer pain.Results After treatment,there was no significant difference in VAS scores and quality of life scores between control group A and control group B(P>0.05).The patients in the treatment group had significantly higher VAS scores and quality of life scores than those in the control group A and the control group B,and the difference was statistically significant(P<0.05);There was no significant difference in the incidence of complications between the control group B and the treatment group,and the difference was not statistically significant(P>0.05);The incidence of complications in the control group A was higher than that in the control group B and the treatment group,and the difference was statistically significant(P<0.05).Conclusion The application of Huaji Dingtong powder applied topically plus oral tramadol hydrochloride sustained-release tablets in patients with liver cancer can effectively relieve pain and improve the quality of life of patients.It is worthy of popularization and application in the clinic.