预注右旋美托咪啶用于喉显微手术麻醉的临床观察

Clinical Observation of Pre-injection of Dexmedetomidine for Anesthesia of Laryngeal Microsurgery

目的分析预注右旋美托咪啶用于喉显微手术麻醉的临床效果。方法选取在我院接受喉显微手术治疗的患者114例,选取时间为2017年1月-2019年3月,随机将其分为2组,即对照组、观察组,各57例,对照组行常规麻醉,观察组在常规麻醉前预注右旋美托咪啶。结果观察组患者的完全清醒时间、睁眼时间、拔管时间等麻醉相关指标,明显低于对照组,差异具有统计学意义,P <0.05;观察组患者在麻醉前、麻醉诱导后、手术开始5 min、手术结束时的心率与平均静脉压,与对照组患者对比,差异具有统计学意义,P <0.05。结论接受喉显微手术治疗的患者在麻醉前预注右旋美托咪啶,可以起到良好的镇静效果。

Objective To analyze the clinical effect of pre-filled dexmedetomidine for laryngeal microsurgery. Methods A total of 114 patients who underwent laryngeal microsurgery in our hospital were enrolled. The patients were randomly selected from January 2017 to March 2019. They were randomly divided into two groups, control group and observation group, 57 cases each. The group underwent routine anesthesia, and the observation group pre-filled dexmedetomidine before routine anesthesia. Results The anesthesia-related indicators such as complete waking time, blink time and extubation time in the observation group were significantly lower than those in the control group, and the difference was statistically significant(P<0.05). The observation group was pre-anesthesia, after anesthesia induction, and surgery. The heart rate and mean venous pressure at the end of 5 minutes and at the end of the operation were compared with those in the control group. The difference was statistically significant(P<0.05). Conclusion Patients receiving laryngeal microsurgery pre-injection of dexmedetomidine before anesthesia can have a good sedative effect.