全甲状腺切除术与次全切术治疗分化型甲状腺癌的临床疗效比较

Comparison of Clinical Effect of Total Thyroidectomy and Subtotal Resection in Treatment of Differentiated Thyroid Carcinoma

目的比较全甲状腺切除术与次全切术治疗分化型甲状腺癌患者的疗效。方法回顾性分析2014年3月至2017年12月江苏省东海县中医院收治的82例分化型甲状腺癌患者,按以全切除和次切除的区别分为观察组和对照组,每组41例,分别接受全甲状腺切除术治疗和次全切术治疗。观察两组患者的临床疗效。结果与对照组相比,观察组患者术中出血量更少,手术时间更短,术后并发症发生率更低,局部复发和远处转移发生率更低,差异均有统计学意义(P<0.05)。结论全甲状腺切除术与次全切术均是治疗分化型甲状腺癌的有效方法,在近期、远期疗效表现上存在着一定的差异。在临床治疗应用的过程中,需要从患者的个体情况出发,充分考量不同手术方法的优势和不足,做出正确的选择。

Objective To compare the effects of total thyroidectomy or subtotal thyroidectomy on patients with differentiated thyroid carcinoma.Methods From March 2014 to December 2017,82 cases with differentiated thyroid carcinoma admitted to Donghai County Hospital of Traditional Chinese Medicine were assigned to the observation group(treated with total thyroidectomy)and the control group(treated with subtotal thyroidectomy),41 cases in each group.The clinical effects of the two groups was compared.Results Compared with the control group,the observation group had less intraoperative blood loss,shorter operation time,higher incidence of postoperative complications,lower incidence of local recurrence and distant metastasis,all of which were statistically significant(P<0.05).Conclusion Total thyroidectomy and subtotal thyroidectomy were effective for the treatment of differentiated thyroid carcinoma,but there were some differences in the shortterm and long-term effects.In the clinical treatment,it is necessary to fully consider the advantages and disadvantages of different surgical methods from the individual case of the patient,and make the right choice.