摘要
随着生活水平的提高和保健意识的增强,丹参作为一种常见并可用于制备保健食品的大宗药材,越来越受到国内外诸多学者的关注。该文以国家药品监督管理局(NMPA)食品网站公布的丹参保健食品作为研究对象,对其剂型、功效成分、保健功能及中药组方等方面进行梳理与分析;应用SPSS Modeler 15. 0中Apriori算法模块对丹参保健食品的组方规律进行探究。结果发现胶囊剂最为普遍(约占55. 34%),冲剂和饮料较为少见。保健功能方面以辅助降血脂、对化学性肝损伤有辅助保护功能、增强免疫力和祛黄褐斑为主;92例辅助降血脂的丹参保健食品中,常见的中药组合为丹参-绞股蓝-葛根;55例对化学性肝损伤有辅助保护功能的丹参保健食品中,常见的中药组合为丹参-葛根-五味子;54例增强免疫力的丹参保健食品中,常见的中药组合为丹参-黄芪-枸杞子;46例祛黄褐斑的丹参保健食品中,常见的中药组合为丹参-当归-葡萄籽。具有不同保健功能的丹参保健食品在方剂配伍的选择上,基本符合中医辨证论治和现代医学理论,可为精准、高效地研发此类保健食品提供借鉴和依据。
With the improvement of living standard and enhancement of health consciousness,Salviae Miltiorrhizae Radix et Rhizoma,as a common medicinal material that can be widely used in health food,is focused an increasing number of scholars’ attention at home and abroad. Based on Salviae Miltiorrhizae Radix et Rhizoma health food published by the food website of National Medical Products Administration( NMPA),this paper combs and analyzes their dosage forms,functional components,health-care functions and prescriptions of traditional Chinese medicine( TCM). Meanwhile,the Apriori algorithm module in SPSS Modeler 15. 0 is used to explore the formulation rules of Salviae Miltiorrhizae Radix et Rhizoma health food. The results showed that capsules was the most common( about 55. 34%),and the infusions and beverages were rare. In the aspect of health-care function,it is mainly used to auxiliary hypolipidemic,auxiliary protective function to chemical liver injury,enhance immunity and dispel chloasma. Among 92 cases of the health food with auxiliary hypolipidemic,the common combination of TCM was Salviae Miltiorrhizae Radix et Rhizoma-Gynostemmatis Pentaphylli Herba-Puerariae Lobatae Radix. Among 55 cases of the health food with auxiliary protective function to chemical liver injury,the common combination of TCM was Salviae Miltiorrhizae Radix et Rhizoma-Puerariae Lobatae Radix-Schisandrae Chinensis Fructus. Among 54 cases of the health food with immune-enhancing,the common combination of TCM was Salviae Miltiorrhizae Radix et Rhizoma-Astragali Radix-Lycii Fructus. Among 46 cases of the health food with dispelling chloasma,the common combination of TCM was Salviae Miltiorrhizae Radix et Rhizoma-Angelicae Sinensis Radix-grape seeds. The selection of prescription compatibility of Salviae Miltiorrhizae Radix et Rhizoma health food with different health-care functions is basically consistent with the TCM treatment with syndrome differentiation theory and modern medical theory. This article interprets the application of Salviae Miltiorrhizae Radix et Rhizoma health food from the perspective of dosage forms,functional components,health-care functions and compatibility of prescriptions,which can provide a basis and reference for precise and efficient research and development of this kind of health food.
作者
王艳宏
樊建
李洪晶
栾宁
盛开
陈大忠
WANG Yan-hong;FAN Jian;LI Hong-jing;LUAN Ning;SHENG Kai;CHEN Da-zhong(Heilongjiang University of Chinese Medicine,Harbin 150040,China)
出处
《中国实验方剂学杂志》
CAS
CSCD
北大核心
2020年第6期168-177,共10页
Chinese Journal of Experimental Traditional Medical Formulae
基金
国家自然科学基金项目(81473359)
黑龙江中医药大学科研基金项目(2018jkcy03)。
关键词
丹参
保健食品
保健功能
剂型
辅助降血脂
祛黄褐斑
增强免疫力
Salviae Miltiorrhizae Radix et Rhizoma
health food
health-care function
dosage form
auxiliary hypolipidemic
dispelling chloasma
immune-enhancing