化疗并发症预警模型在非小细胞肺癌化疗患者中的应用

Application of early warning model of chemotherapy complications in nursing care of patients with non-small cell lung cancer during chemotherapy

目的探讨化疗并发症预警模型在非小细胞肺癌患者化疗期护理中的应用效果。方法采用便利抽样法,选取2016年1月—2019年2月郑州大学第一附属医院胸外科收治的非小细胞肺癌化疗患者106例为研究对象,按照入院时间分为对照组(n=52)和观察组(n=54)。对照组给予常规护理,观察组通过化疗并发症预警模型进行护理。采用汉密顿焦虑量表(HAMA)、汉密顿抑郁量表(HAMD)和癌症患者生命质量测定量表(EORTC QLQ-C30)比较两组干预效果,统计两组化疗期间并发症发生情况。结果观察组化疗期间并发症总发生率26.92%(14/52),对照组为46.15%(24/52),差异有统计学意义(χ2=4.147,P<0.05)。干预后3个月,观察组患者HAMA(9.87±4.25)分、HAMD(15.54±3.58)分,均低于对照组,差异均有统计学意义(t值分别为4.738、8.296;P<0.05)。观察组干预后功能评分、症状评分、整体生活质量评分、单项测量项目评分高于对照组,差异有统计学意义(P<0.05)。结论在非小细胞肺癌化疗期间通过化疗并发症预警模型进行护理能够降低患者化疗并发症发生率,缓解患者负性情绪,提高生活质量,值得临床推广应用。

Objective To explore the application effect of early warning model of chemotherapy complications in nursing care of non-small cell lung cancer during chemotherapy.Methods By using convenient sampling method,106 patients with non-small cell lung cancer treated by chemotherapy in the Thoracic Surgery Department of the First Affiliated Hospital of Zhengzhou University from January 2016 to February 2019 were selected as the study objects.According to the time of admission,they were divided into the control group(n=52)and the observation group(n=54).The control group was given routine nursing care during chemotherapy,while the observation group was given nursing care through early warning model of chemotherapy complications during chemotherapy.Hamilton Anxiety Scale(HAMA),Hamilton Depression Scale(HAMD)and European Organization for the Research and Treatment of Cancer QLQ-C30(EORTCQLQ-C30)were used to compare the intervention effect of the two groups,and the incidence of complications during chemotherapy was counted.Results The total incidence of complications was 26.92%(14/52)in the observation group and 46.15%(24/52)in the control group,the difference was statistically significant(χ2=4.147,P<0.05).Three months after the intervention,HAMA(9.87±4.25)and HAMD(15.54±3.58)in the observation group were lower than those in the control group;the differences were statistically significant(t=4.738,8.296;P<0.05).The functional score,symptom score,overall quality of life score and single measurement item score of the observation group were higher than those of the control group with statistical differences(P<0.05).Conclusions During chemotherapy for non-small cell lung cancer,nursing through the early warning model of chemotherapy complications can reduce the incidence of chemotherapy complications,alleviate the negative emotions of patients,and improve the quality of life,which is worthy of clinical application.