醒脑静注射液治疗老年脑梗死患者的效果及对脑血流动力学的影响

Effect of Xingnaojing Injection in Treatment of Elderly Patients with Cerebral Infarction and Influece on Cerebral Hemodynamics

目的:探究老年脑梗死患者应用醒脑静注射液治疗的临床效果及对脑血流动力学的影响。方法:选取2015-2018年本院收治的102例老年脑梗死患者,随机分为观察组与对照组,每组51例。对照组应用复方丹参注射液治疗,观察组应用醒脑静注射液治疗。对比两组治疗前后大脑前动脉(ACA)、大脑中动脉(MCA)、大脑后动脉(PCA)、基底动脉(BA)的平均血流速度(Vm)等脑血流动力学指标变化与治疗效果,并记录治疗过程中的不良反应。结果:观察组治疗后总有效率为78.43%,明显高于对照组的58.82%(P<0.05);两组治疗后ACA、MCA、PCA、BA的Vm均较治疗前显著提升(P<0.05),且观察组较对照组均显著提升(P<0.05)。两组患者均未发生明显不良反应。结论:醒脑静注射液治疗老年脑梗死患者,能有效促脑血流动力,提高恢复效率,改善治疗效果。

Objective:To explore the effect of Xingnaojing Injection in the treatment of elderly patients with cerebral infarction and influece on cerebral hemodynamics.Method:A total of 102 elderly patients with cerebral infarction admitted to our hospital from 2015 to 2018 were randomly divided into the observation group and the control group,51 cases in each group.The control group was treated with Compound Danshen Injection,and the observation group was treated with Xingnaojing Injection.Before and after treatment,the Vm changes of ACA,MCA,PCA and BA of two groups were compared,and the adverse reactions of two groups were recorded.Result:After treatment,the total effective rate of the observation group was 78.43%,it was significantly higher than 58.82%of the control group(P<0.05).After treatment,the ACAVm,MCAVm,PCAVm and BAVm of two groups were significantly increased compared with those before treatment(P<0.05),and the observation group were significantly increased compared with the control group(P<0.05).There were no obvious adverse reactions in two groups.Conclusion:Xingnaojing Injection can effectively improve cerebral hemodynamics,recovery efficiency and therapeutic effect in elderly patients with cerebral infarction.