探讨益生菌预防新生儿抗生素相关性腹泻效果

Effect of probiotics on prevention of antibiotic related diarrhea in neonates

目的:探讨益生菌预防新生儿抗生素相关性腹泻效果。方法:2017年2月-2018年2月收治接受抗生素治疗的新生儿80例,随机分为两组,各40例。对照组单纯予以抗感染治疗;观察组在抗感染的基础上辅以益生菌治疗。比较两组治疗效果。结果:观察组治疗周期明显短于对照组,观察组患儿治疗期间腹泻和严重腹泻明显低于对照组,差异均有统计学意义(P<0.05)。结论:接受抗生素治疗的新生儿加用益生菌治疗,不仅能够缩短治疗周期,还能预防新生儿抗生素相关性腹泻的发生,效果显著。

Objective:To explore the effect of probiotics on the prevention of antibiotic associated diarrhea in neonates.Methods:80 newborns treated with antibiotics were selected from February 2017 to February 2018,they were randomly divided into the two groups with 40 cases in cach group.The control group was only given anti infection treatment,the observation group was treated with probiotics on the basis of anti infection.The therapeutic effects of the two groups were compared.Results:The treatment cycle of the observation group was significantly shorter than that of the control group,the incidence of diarrhea and severe diarrhea in the observation group was significantly lower than that in the control group,the differences were statistically significant(P<0.05).Conclusion:Adding probiotics to newborns receiving antibiotic treatment can not only shorten the treatment cycle,but also prevent the occurrence of antibiotic related diarrhea,the effect is significant.