MIC反应器处理抗生素发酵废液的研究

Treatment of Antibiotic Fermentation Waste Liquid by MIC Reactor

采用逐步提高抗生素浓度和有机负荷(OLR)的方法,考察改进型内循环厌氧反应器(MIC反应器)对含万古霉素(VA)发酵废液的处理效果,并对微生物群落进行分析。结果表明,污泥经过驯化后,MIC反应器对VA发酵废液有较好的处理能力,当进水VA浓度为70 mg/L左右、水力停留时间(HRT)为4 d时,对MIC反应器运行没有抑制效应,此时COD去除率约为90%,VA去除率达到90%以上;当HRT为2 d、进水OLR为25 kgCOD/(m^3·d)时,MIC反应器对VA发酵废液的COD去除负荷最大,为19.5 kg/(m^3·d)。通过微生物多样性检测结果发现,细菌群落在门水平上的优势菌为Bacteroidetes和Firmicutes。

By gradually increasing antibiotics concentration and organic loading rate (OLR),the treatment efficiency of modified internal circulation anaerobic reactor (MIC reactor) on the vancomycin (VA)-containing antibiotic fermentation waste liquid was investigated,and the microbial community was analyzed. The MIC reactor had good performance for the treatment of VA-containing fermentation waste liquid after the domestication of the sludge. When the influent VA concentration was about 70 mg/L and hydraulic retention time (HRT) was 4 days,no inhibitory effect on the operation of the MIC reactor was observed. At this time,the COD removal rate was about 90% and the VA removal rate was over 90%.When HRT was 2 days and OLR was 25 kgCOD/ (m^3·d),the maximum COD removal loading of VAcontaining fermentation waste liquid was achieved by the MIC reactor,which was 19. 5 kg/ (m^3·d).The result of microbial diversity analysis showed that Bacteroidetes and Firmicutes were the dominant bacteria at the phylum level.