恶性肿瘤患者医院感染的特点及危险因素分析

Characteristics and Risk Factors of Nosocomial Infectionsin Patients with Malignant Tumor

目的探讨恶性肿瘤患者发生医院感染的特点及危险因素。方法采用卡方检验分析恶性肿瘤患者医院感染的临床特点;单因素及多因素Logistic回归分析恶性肿瘤患者医院感染的危险因素。结果恶性肿瘤患者医院感染部位以肺部感染为主(48.48%);病原菌依次为革兰阴性菌(70.8%)、革兰阳性菌(21.3%)及真菌(7.9%)。单因素和多因素Logistic回归分析显示,性别、年龄、住院时间、肿瘤分期、侵入性操作是独立危险因素(均为P<0.05)。结论恶性肿瘤患者以男性、≥65岁、住院时间>30 d、肿瘤分期Ⅳ期以下、有侵入性操作等为发生医院感染的高危因素。

Objective To investigate the characteristics and risk factors of nosocomial infection in patients with malignant tumors.Methods Chi-square test was used to analyze the clinical characteristics of nosocomial infection in patients with malignant tumors.Univariate and multivariate logistic regression were used to analyze the risk factors of nosocomial infection in patients with malignant tumors.Results Pulmonary infection(48.48%)was the main infection site in patients with malignant tumor.The pathogenic bacteria were gram negative(70.8%),gram positive(21.3%)and fungal(7.9%),respectively.Univariate and multivariate logistic regression analysis showed that gender,age,length of hospital stay,cancer's clinical stage,and invasive surgery were independent risk factors(P<0.05).Conclusion Male,age of 65 or older,30 days or longer in hospital,cancer clinical stageⅠthroughⅢ,and invasive procedures are risk factors for nosocomial infection in patients with malignant tumors.